Does Ozempic Need To Be Refrigerated? Proper Storage Guidelines!

By Kendra Reed

Updated On

Ozempic is an injection that helps improve blood sugar levels in adults with type 2 diabetes. It is a weekly injection that helps manage blood sugar levels, along with diet and exercise. This formula is also said to lower the risk of cardiovascular diseases, such as heart attack, stroke, heart disease, and death.

Even though it is not a weight loss supplement, it still may help reduce some weight. Ozempic, also known as semaglutide, is approved by the FDA to be effective against diabetes. This weekly injection works to help the pancreas make more insulin. Since Ozempic comes as an injection, proper storing is necessary to ensure its quality, effectiveness, and safety. 

Most people have doubts about whether or not to refrigerate Ozempic. Well, unopened Ozempic should be refrigerated until the first use, and after using it, it can be kept in the fridge or at room temperature. Not only regarding Ozempic but all medications should be stored properly to keep them safe and effective.

Refer to the pharmacist for the correct instructions on storing medications. Note that, poor storage conditions can cause the medication to degrade, lose its potency, contaminate, and even cause harm to the patients. 

Understanding Ozempic

Ozempic is a medicine for type 2 diabetes. It helps improve blood sugar levels in adults while reducing the risk of cardiovascular diseases. This formula also reduces the risk of heart attacks, stroke, and other heart diseases. Ozempic works to manage blood sugar levels by helping the pancreas make more insulin and decreasing the amount of sugar the liver makes.

Proper Storage Guidelines for Ozempic

It slows the rate of food passing through the body, which makes one feel fuller and reduces appetite, thus resulting in healthy weight loss. Ozempic is a weekly injection that should be used together with exercise and diet. Remember, this formula is not suitable for those with type 1 diabetes mellitus. 

Ozempic has undergone clinical tests and is FDA-approved to be effective in managing blood sugar levels. It is not approved for weight loss as it directly does not help lose weight. However, many physicians prescribe Ozempic as a weight loss supplement.

As for how to use Ozempic, it should be injected under the skin, either on your stomach (abdomen), upper arm, or thigh. Do not inject Ozempic into a muscle or vein and do not use the same spot for the next injection. Instead, choose a different site for each injection. It is best to use Ozempic once a week on the same day each week. 

General storage requirements for Ozempic

Ozempic should be stored in the refrigerator prior to first use until expiration but do not freeze the medication. Do not use medications that have expired. After the first use, Ozempic should be stored at room temperature.

If you are storing at room temperature, the temperature should be between 59 degrees Fahrenheit to 86 degrees Fahrenheit (15 degrees Celsius to 30 degrees Celsius) or 36 degrees Fahrenheit to 46 degrees Fahrenheit (2 degrees Celsius to 8 degrees Celsius) in the refrigerator.

Ensure you follow the correct storage instructions to protect the medicines from excessive humidity and moisture. Exposure to excess humidity and moisture can result in mold growth, degrading of active ingredients, or making them ineffective. 

Refrigeration of Ozempic: The basics

Ozempic has a specific storage requirement, as it is an injectable medication. Unopened Ozempic should be stored in the refrigerator up to their expiration date. After the first use, you can refrigerate it or store it at room temperature.

If you are refrigerating Ozempic, the temperature should be between 36 degrees Fahrenheit to 46 degrees Fahrenheit (2 degrees Celsius to 8 degrees Celsius). Ozempic can be refrigerated as long as the expiration date. 

Room temperature storage of Ozempic

After the first use, Ozempic can be stored at room temperature for up to 56 days. Ozempic is only safe to leave unrefrigerated if it is stored at a room temperature between 59 degrees Fahrenheit to 86 degrees Fahrenheit (15 degrees Celsius to 30 degrees Celsius).

Keep away from excessive heat and sunlight, as it cause damage to the medications. Keep the pens in a temperature-controlled environment to ensure they are safe and effective to use. 

Signs of improperly stored Ozempic

Signs of improperly stored Ozempic, include;

  • The contents inside the packaging feel warm.
  • Cloudy or discoloration in the medication in the pen’s window.
  • You notice any particles in the liquid (medication).
  • The ice packs used to store Ozempic to keep them cold are melted. 
  • If the package was out in the heat or sunlight. 

Common mistakes in storing Ozempic

After 56 days, it will expire, and you will need to start using a new Ozempic pen. Here are some of the common mistakes in storing Ozempic;

  • Not disposing of the medication properly even if there is a small portion of medicine remaining in the pen. 
  • Avoid storing Ozempic in places like bathroom cabinets or car gloveboxes where temperature fluctuations can occur. 
  • Exposing Ozempic to excessive heat or direct sunlight. 
  • Not inspecting the medication before each injection to ensure they are not cloudy or discolored. 
  • Keeping the medicine in the freezer.

Conclusion

Ozempic is a medicine for adults struggling with type 2 diabetes. It comes in an injection form and helps manage blood sugar levels, lower the risk of cardiovascular diseases, and aid in weight loss. This medication works well with diet and exercise.

Ozempic should be injected under the skin, either on your stomach (abdomen), upper arm, or thigh, and do not inject Ozempic into a muscle or vein. Do not use the same spot for the next injection. Instead, choose a different site for each injection. Ozempic should be refrigerated before the first use, and after the first use, it should be stored at room temperature away from excess heat or direct sunlight. The room temperature for storing Ozempic should be between 59 degrees Fahrenheit to 86 degrees Fahrenheit (15 degrees Celsius to 30 degrees Celsius) or refrigerated at 36 degrees Fahrenheit to 46 degrees Fahrenheit (2 degrees Celsius to 8 degrees Celsius).

Follow the storage instructions strictly to prevent the medications from going bad and to prevent exposure to excess humidity and moisture, as it can result in mold growth, degrading of active ingredients, or making them ineffective. Look for signs of improper storage and do not use the medication if is not stored properly. Also, do not use Ozempic if it is expired, frozen, or exposed to excess heat. To keep the medication safe, store it in a temperature-controlled environment. 

Frequently Asked Questions

1. What happens to Ozempic if it’s not refrigerated?

If Ozempic is left unrefrigerated, it may go bad even before the expiration date. The medication may be unsafe and ineffective due to improper storage. 

2. How do you carry Ozempic while traveling?

Try storing Ozempic in an insulated travel container and ensure the medication has no direct contact with ice or excess heat. Do not freeze it or leave it in direct sunlight. When you arrive at the destination, transfer Ozempic pens to a refrigerator.

3. What happens if my semaglutide gets warm?

Do not expose Ozempic to high temperatures, as the medication may go bad. They can be safely used if they are stored at room temperature between 59 degrees Fahrenheit to 86 degrees Fahrenheit (15 degrees Celsius to 30 degrees Celsius) for up to 56 days. 

4. Can I travel with Ozempic without refrigeration?

Unopened Ozempic should be refrigerated before the first use, and yes, you can travel without refrigerating Ozempic. Ensure you keep the medication in an insulated travel case and keep it away from fluctuating temperatures. Also, store Ozempic in a refrigerator once you reach the destination. 

5. What happens if you accidentally freeze Ozempic?

Do not use Ozempic if it is frozen, and you need to throw it away, as it is not suitable for use anymore. 

Kendra Reed

Dr. Kendra Reed is a dedicated general medicine physician with 7 years of clinical experience. After graduating from medical school, she completed her residency in internal medicine, developing a well-rounded skillset in diagnosing and treating a diverse range of conditions. Patients appreciate Dr. Reed's warm bedside manner and commitment to providing comprehensive, personalized care. In addition to her clinical work, she is actively involved in community outreach programs, educating the public on important health topics. Dr. Reed is known for her ability to establish trusting relationships with her patients and help them achieve their wellness goals.

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