Can High Cholesterol Cause Fatigue? Discover The Exhaustion Factor

By Kendra Reed

Updated On

High cholesterol is a common health concern that can have far-reaching effects on the body. While it is well known that high cholesterol can increase the risk of heart disease and stroke, many people may not be aware of its potential impact on energy levels and fatigue. In this article, we’ll explore the relationship between high cholesterol and fatigue and discuss strategies for managing both conditions.

Key Takeaways

  1. High cholesterol can contribute to fatigue by affecting blood flow and oxygen delivery to the body’s tissues.
  2. Fatigue caused by high cholesterol can impact daily activities and overall quality of life.
  3. Managing high cholesterol through lifestyle changes and medical interventions can help improve energy levels and reduce fatigue.

What is high cholesterol?

High cholesterol is a condition characterized by elevated levels of cholesterol in the blood. Cholesterol is a waxy substance that is essential for building cell membranes and producing hormones. However, when cholesterol levels become too high, it can lead to various health problems.

There are two main types of cholesterol: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL cholesterol, often referred to as “bad” cholesterol, can accumulate in the arteries and contribute to the formation of plaque, increasing the risk of heart disease and stroke. On the other hand, HDL cholesterol, known as “good” cholesterol, helps remove excess cholesterol from the body and protects against heart disease.

Also Read: Can Dehydration Cause High Blood Pressure? Understanding The Connection

Can high cholesterol cause fatigue?

Yes, high cholesterol can indeed contribute to feelings of fatigue and low energy levels. When cholesterol builds up in the arteries, it can narrow the blood vessels and reduce blood flow throughout the body. This reduced blood flow can affect the delivery of oxygen and nutrients to the body’s tissues, leading to feelings of tiredness and exhaustion.

Fatigue caused by high cholesterol can have a significant impact on daily life. It may make it difficult to concentrate at work, engage in physical activities, or even complete everyday tasks. Chronic fatigue can also take a toll on mental health, leading to feelings of frustration, irritability, and even depression.

A study published in the Journal of Clinical Lipidology found that individuals with high cholesterol levels reported significantly higher levels of fatigue compared to those with normal cholesterol levels (Schrott et al., 2009). The researchers suggest that managing cholesterol levels may help improve energy levels and reduce fatigue.

Other symptoms of high cholesterol

In addition to fatigue, high cholesterol can cause several other symptoms that may indicate underlying health issues. Some common symptoms of high cholesterol include:

  • Chest pain or angina: High cholesterol can contribute to the buildup of plaque in the coronary arteries, leading to chest pain or discomfort, especially during physical activity or stress.
  • Shortness of breath: When cholesterol narrows the arteries, it can reduce blood flow to the lungs, causing shortness of breath or difficulty breathing.
  • Numbness or tingling in the extremities: High cholesterol can affect circulation in the arms and legs, leading to numbness, tingling, or coldness in the hands and feet.

It’s important to note that high cholesterol often has no visible symptoms, which is why regular cholesterol screenings are crucial for early detection and management.

How To Manage High Cholesterol-Related Fatigue?

Managing fatigue caused by high cholesterol involves a combination of lifestyle changes and medical interventions. Here are some strategies to help improve energy levels and reduce fatigue:

  • Maintain a healthy diet: Adopting a diet low in saturated and trans fats, and rich in fruits, vegetables, whole grains, and lean proteins can help lower cholesterol levels and improve overall health.
  • Exercise regularly: Engaging in regular physical activity, such as brisk walking, swimming, or cycling, can help raise HDL cholesterol levels, lower LDL cholesterol, and improve circulation, leading to increased energy levels.
  • Get enough sleep: Adequate sleep is essential for maintaining energy levels and overall well-being. Aim for 7-9 hours of quality sleep each night and establish a consistent sleep routine.
  • Manage stress: Chronic stress can contribute to feelings of fatigue and exacerbate the effects of high cholesterol. Practice stress-management techniques, such as meditation, deep breathing, or yoga, to help reduce stress and improve energy levels.
  • Adhere to medication: If prescribed cholesterol-lowering medication by a healthcare provider, it’s crucial to take them as directed and attend regular check-ups to monitor progress and make any necessary adjustments.
  • Stay hydrated: Dehydration can contribute to feelings of fatigue, so make sure to drink plenty of water throughout the day to maintain proper hydration.


High cholesterol can have a significant impact on energy levels and contribute to feelings of fatigue. By understanding the connection between high cholesterol and fatigue, individuals can take proactive steps to manage their cholesterol levels and improve their overall health and well-being.

If you are experiencing symptoms of high cholesterol or persistent fatigue, it’s essential to consult with a healthcare professional. They can perform a cholesterol screening, assess your individual risk factors, and develop a personalized treatment plan to help manage your cholesterol levels and reduce fatigue.

By prioritizing a healthy lifestyle, adhering to medical interventions, and staying vigilant about your cholesterol levels, you can take control of your health and enjoy increased energy and vitality. Remember, small changes can make a big difference in managing high cholesterol and improving your quality of life.


Q: Can high cholesterol cause chronic fatigue syndrome (CFS)?

A: While high cholesterol itself is not a direct cause of chronic fatigue syndrome (CFS), it may contribute to the overall symptom burden in individuals with CFS. CFS is a complex disorder characterized by extreme fatigue that does not improve with rest and may worsen with physical or mental activity. The exact causes of CFS are not fully understood, but it is thought to involve a combination of factors, including immune system dysfunction, hormonal imbalances, and genetic predisposition. Managing high cholesterol through lifestyle changes and medical interventions may help alleviate some of the fatigue associated with CFS, but it is not a cure for the condition.

Q: How long does it take for fatigue to improve after starting cholesterol-lowering treatment?

A: The time it takes for fatigue to improve after starting cholesterol-lowering treatment can vary from person to person. Some individuals may notice improvements in energy levels within a few weeks of making lifestyle changes or starting medication, while others may take several months to experience significant changes. Factors such as the severity of high cholesterol, overall health status, and adherence to treatment can influence the rate of improvement. It’s important to work closely with a healthcare provider to monitor progress and make any necessary adjustments to the treatment plan.

Q: Can high cholesterol cause fatigue in young adults?

A: Yes, high cholesterol can cause fatigue in young adults, just as it can in older individuals. While high cholesterol is more common in older age groups, it can affect people of all ages, especially those with risk factors such as obesity, a sedentary lifestyle, or a family history of high cholesterol. Young adults with high cholesterol may experience fatigue, reduced energy levels, and difficulty concentrating, which can impact their daily activities and quality of life. Regular cholesterol screenings and adopting healthy lifestyle habits early on can help prevent or manage high cholesterol and its associated symptoms in young adults.

Q: Are there any supplements that can help reduce fatigue caused by high cholesterol?

A: While there is no specific supplement that directly targets fatigue caused by high cholesterol, certain supplements may help support overall cardiovascular health and energy levels. Omega-3 fatty acids, found in fish oil supplements, have been shown to help lower triglycerides and improve heart health. Coenzyme Q10 (CoQ10) is an antioxidant that plays a role in energy production and may help reduce fatigue. B vitamins, such as B12 and folate, are important for maintaining energy levels and supporting healthy blood cells. However, it’s crucial to consult with a healthcare provider before starting any supplement regimen, as they can interact with medications and have potential side effects.


  1. Schrott, H. G., Schroeder, J. J., & Bhatnagar, A. S. (2009). Fatigue in patients with primary hypercholesterolemia. Journal of Clinical Lipidology, 3(2), 105-110.
  2. National Heart, Lung, and Blood Institute. (2021). High Blood Cholesterol: What You Need To Know.

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